PLAY AND LEARN: A NEW LOOK AT LUDICITY IN THE FIRST YEAR OF ELEMENTARY SCHOOL



Decreased Mdm2 expression inhibits tumor development and extends survival independent of Arf and dependent on p53.

Inactivation of the Arf-Mdm2-p53 tumor suppressor pathway is a necessary event for tumorigenesis.Arf controls Mdm2, which in turn regulates p53, but Arf and Mdm2 also have p53-independent functions that affect tumor development.Moreover, inhibition of oncogene-induced tumorigenesis relies on Arf and p53, but the requirements of Arf and p53 in tumor

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Codifying unstructured data: A Natural Language Processing approach to extract rich data from clinical letters

ABSTRACT Objectives Electronic healthcare records (EHR) are the main data sources that facilitate epidemiology research.Routinely collected data such as primary and secondary care are now easily linked to produce novel and high impact research.There are, however, rich data locked in the free text of clinical letters that are not otherwise translate

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